CGS 27023A |CAS:161314-82-5 Probechem Biochemicals

Chemical Structure : CGS 27023A

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CGS 27023A (MMI 270;CGS 27023 Hcl)

货号: PC-62946Not For Human Use, Lab Use Only.

CGS 27023A (MMI 270) is a potent, orally active MMP inhibitor with Ki of 8-43 nM for MMP1/2/3/9.

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1 g		Get quote

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生物&药学活性

CGS 27023A (MMI 270) is a potent, orally active MMP inhibitor with Ki of 8-43 nM for MMP1/2/3/9.
CGS 27023A shows growth-inhibitory effects in breast carcinoma, prostate, bladder, colon, lung adenocarcinoma, glioblastoma, and ovarian carcinoma cell line.
CGS 27023A protects the cartilage proteoglycan matrix in a partial meniscectomy model of osteoarthritis in rabbits.

物理化学性质&存储条件

分子量	429.916
分子式	C18H24ClN3O5S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Butanamide, N-hydroxy-2-[[(4-methoxyphenyl)sulfonyl](3-pyridinylmethyl)amino]-3-methyl-, monohydrochloride, (2R)- (9CI)

参考文献

1. Qian LW, et al. Clin Cancer Res. 2002 Apr;8(4):1223-7.

2. Levitt NC, et al. Clin Cancer Res. 2001 Jul;7(7):1912-22.

3. Eskens FA, et al. Clin Cancer Res. 2000 Feb;6(2):431-3.

4. Rossello A, et al. Bioorg Med Chem. 2004 May 1;12(9):2441-50.

CGS 27023A (MMI 270;CGS 27023 Hcl)

生物&药学活性

物理化学性质&存储条件

参考文献

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CGS 27023A (MMI 270;CGS 27023 Hcl)

生物&药学活性

物理化学性质&存储条件

参考文献

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