CGS 21680 hydrochloride |CAS:124431-80-7 Probechem Biochemicals

Chemical Structure : CGS 21680 hydrochloride

CAS No.: 124431-80-7

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CGS 21680 hydrochloride (CGS-21680 Hydrochloride;CGS21680 Hydrochloride)

货号: PC-43386Not For Human Use, Lab Use Only.

CGS 21680 hydrochloride is a specific adenosine A2A subtype receptor agonist with Ki of 27 nM.

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5 mg	￥780	In stock
10 mg	￥1180	In stock
25 mg	￥1980	In stock
50 mg	￥3280	In stock
100 mg		Get quote

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生物&药学活性

CGS 21680 hydrochloride is a specific adenosine A2A subtype receptor agonist with Ki of 27 nM.
CGS 21680 significantly upregulates CD39 and CD73 expression, accelerates the ATP hydrolysis and adenosine generation.
CGS 21680 reduces the number of infiltrated granulocytes into the ischemic tissue in rat model of transient cerebral ischemia.

物理化学性质&存储条件

分子量	535.9806
分子式	C23H30ClN7O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 20 mg/mL
Chemical Name/SMILES	3-(4-(2-((6-amino-9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxytetrahydrofuran-2-yl)-9H-purin-2-yl)amino)ethyl)phenyl)propanoic acid hydrochloride

参考文献

1. Nekooeian AA, et al. Br J Pharmacol. 1998 Apr;123(8):1666-72.

2. Phillis JW, et al. Brain Res. 1990 Feb 19;509(2):328-30.

3. Komaki S, et al. Neurosci Lett. 2012 Jul 26;522(1):21-4.

4. Melani A, et al. Brain Res. 2014 Mar 10;1551:59-72.

CGS 21680 hydrochloride (CGS-21680 Hydrochloride;CGS21680 Hydrochloride)

生物&药学活性

物理化学性质&存储条件

参考文献

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CGS 21680 hydrochloride (CGS-21680 Hydrochloride;CGS21680 Hydrochloride)

生物&药学活性

物理化学性质&存储条件

参考文献

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