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首页-小分子抑制剂&激动剂-TGF-beta/Smad-PKC-CGP60474
CGP60474

Chemical Structure : CGP60474

CAS No.: 164658-13-3

CGP60474 (CGP-60474;CGP 60474)

货号: PC-42784Not For Human Use, Lab Use Only.

A potent CDK1 inhibitor with IC50 of 17 nM.

规格 价格 库存 数量
10 mg ¥1120 In stock
50 mg ¥4000 In stock
100 mg ¥6656.0 In stock

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

A potent CDK1 inhibitor with IC50 of 17 nM; exhibits lower potency at CDK2 (IC50=50-80nM) and moderate potency at CDK4 (IC50=700 nM).

物理化学性质&存储条件

分子量 355.8214
分子式 C18H18ClN5O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-Propanol, 3-[[4-[2-[(3-chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-

参考文献

1. Ruetz S, et al. Curr Med Chem Anticancer Agents. 2003 Jan;3(1):1-14.

2. Kuo GH, et al. J Med Chem. 2005 Jul 14;48(14):4535-46.

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