CGP-53716 |CAS:152459-94-4 Probechem Biochemicals

Chemical Structure : CGP-53716

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CGP-53716 (CGP 53716;CGP53716)

货号: PC-70043Not For Human Use, Lab Use Only.

A potent protein tyrosine kinase inhibitor that shows selectivity for PDGFR in vitro and in cells.

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生物&药学活性

A potent protein tyrosine kinase inhibitor that shows selectivity for PDGFR in vitro and in cells; shows selectivity for inhibition of PDGF-mediated events such as PPDGFR autophosphorylation, cellular tyrosine phosphorylation, and c-Fos mRNA induction in response to PDGF stimulation of intact cells.

物理化学性质&存储条件

分子量	381.439
分子式	C23H19N5O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide

参考文献

1. Buchdunger E, et al. Proc Natl Acad Sci U S A. 1995 Mar 28;92(7):2558-62.

2. Major TC, et al. J Pharmacol Exp Ther. 1997 Oct;283(1):402-10.

3. Mayer AM, et al. J Pharmacol Exp Ther. 1996 Nov;279(2):633-44.

CGP-53716 (CGP 53716;CGP53716)

生物&药学活性

物理化学性质&存储条件

参考文献

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CGP-53716 (CGP 53716;CGP53716)

生物&药学活性

物理化学性质&存储条件

参考文献

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