CG-0988 | SARS-CoV-2 3CLpro inhibitor | Probechem Biochemicals

Chemical Structure : CG-0988

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CG-0988 (CG0988)

货号: PC-26746Not For Human Use, Lab Use Only.

CG-0988 is a potent, covalent SARS-CoV-2 3C-like protease (3CLpro) inhibitor with IC50 of 8.5 nM, demonstrates excellent antiviral activity with EC50 of 4.0 nM against Omicron EG.5.1.

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生物&药学活性

CG-0988 is a potent, covalent SARS-CoV-2 3C-like protease (3CLpro) inhibitor with IC50 of 8.5 nM, demonstrates excellent antiviral activity with EC50 of 4.0 nM against Omicron EG.5.1.

物理化学性质&存储条件

分子量	529.57
分子式	C29H28FN5O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(3R,5'S)-1'-((S)-2-(2-(cyclopropanecarbonyl)-7-oxo-1,7-dihydro-6H-pyrrolo[2,3-c]pyridin-6-yl)-4-fluoro-4-methylpentanoyl)-2-oxospiro[indoline-3,3'-pyrrolidine]-5'-carbonitrile

参考文献

1. Tang X, et al. Eur J Med Chem. 2026 Apr 30;314:118889.

CG-0988 (CG0988)

生物&药学活性

物理化学性质&存储条件

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CG-0988 (CG0988)

生物&药学活性

物理化学性质&存储条件

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