CFI02 |CAS:273735-28-7 Probechem Biochemicals

Chemical Structure : CFI02

CAS No.: 273735-28-7

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CFI02 (CFI 02;CFI-02)

货号: PC-35123Not For Human Use, Lab Use Only.

CFI02 (CFI-02) is a specific inhibitor of human cytomegalovirus (HCMV) glycoprotein B-mediated fusion with IC50 of 40 nM against laboratory adapted HCMV strain AD169.

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5 mg	￥1980	In stock
25 mg	￥3980	In stock
100 mg	￥7980	In stock
250 mg		Get quote
1 g		Get quote

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生物&药学活性

CFI02 (CFI-02) is a specific inhibitor of human cytomegalovirus (HCMV) glycoprotein B-mediated fusion with IC50 of 40 nM against laboratory adapted HCMV strain AD169.
CFI02 reduces HCMV yield by >3 logs at 1 uM, and shows no inhibitory activity against closely related betaherpesviruses (including MCMV, simian CMV, and RCMV) (IC50>20 uM) as well as cytotoxic effect (CC50>50 uM).

物理化学性质&存储条件

分子量	491.43
分子式	C18H11F6N5OS2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-(3-(3,5-bis(trifluoromethyl)phenyl)thioureido)phenyl)-1,2,3-thiadiazole-4-carboxamide

参考文献

1. Jones TR, et al. J Virol. 2004 Feb;78(3):1289-300.

2. Bloom JD, et al. Bioorg Med Chem Lett. 2003 Sep 1;13(17):2929-32.

CFI02 (CFI 02;CFI-02)

生物&药学活性

物理化学性质&存储条件

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CFI02 (CFI 02;CFI-02)

生物&药学活性

物理化学性质&存储条件

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