CFI-400437 dihydrochloride

Chemical Structure : CFI-400437 dihydrochloride

CAS No.: 1247000-76-5

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货号: PC-28543Not For Human Use, Lab Use Only.

CFI-400437 dihydrochloride is a potent and selective inhibitors of Polo-like kinase 4 (PLK4) with IC50 of 0.6 nM.

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CFI-400437 dihydrochloride is a potent and selective inhibitors of Polo-like kinase 4 (PLK4) with IC50 of 0.6 nM.

分子量	565.50
分子式	C29H30Cl2N6O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-Methoxy-3-((3-((E)-2-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)vinyl)-1H-indazol-6-yl)methylene)indolin-2-one dihydrochloride

1. Laufer R, et al. J Med Chem. 2013 Aug 8;56(15):6069-87.