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首页-小分子抑制剂&激动剂-GPCR-Adenosine Receptor-CF102
CF102

Chemical Structure : CF102

CAS No.: 163042-96-4

CF102 (Namodenoson, CF-102, 2-Cl-IB-MECA)

货号: PC-22194Not For Human Use, Lab Use Only.

Namodenoson (2-Cl-IB-MECA, CF-102) is a potent, selective A3 adenosine receptor (A3AR) agonist with Ki of 0.33 nM, displays 2500- and 1400-fold selectivity over A1 and A2A receptors respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Namodenoson (2-Cl-IB-MECA, CF-102) is a potent, selective A3 adenosine receptor (A3AR) agonist with Ki of 0.33 nM, displays 2500- and 1400-fold selectivity over A1 and A2A receptors respectively.

物理化学性质&存储条件

分子量 544.73
分子式 C18H18ClIN6O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2S,3S,4R,5R)-5-(2-Chloro-6-((3-iodobenzyl)amino)-9H-purin-9-yl)-3,4-dihydroxy-N-methyltetrahydrofuran-2-carboxamide

参考文献

1. Van Schaick EA et al. Eur J Pharmacol. 1996 Jul 25;308(3):311-4.

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