CE3F4 | EPAC1 inhibitor | Probechem Biochemicals

Chemical Structure : CE3F4

CAS No.: 143703-25-7

加入收藏

CE3F4 (EPAC1 inhibitor CE3F4)

货号: PC-63111Not For Human Use, Lab Use Only.

CE3F4 is a potent, noncompetitive EPAC1 inhibitor that blocks EPAC1-induced Rap1 activation both in cell-free systems and in intact cells and did not influence protein kinase A holoenzyme activity.

规格	价格	库存
10 mg	￥880	In stock
25 mg	￥1480	In stock
50 mg	￥2380	In stock
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

CE3F4 is a potent, noncompetitive EPAC1 inhibitor that blocks EPAC1-induced Rap1 activation both in cell-free systems and in intact cells and did not influence protein kinase A holoenzyme activity.
CE3F4 reduces the exchange activity of Epac1 induced by 007 (2 uM) with IC50 of 23 uM.
CE3F4 is a useful pharmacological tools for determining the biological functions of EPAC1 in a wide range of biological processes.

物理化学性质&存储条件

分子量	351.01
分子式	C11H10Br2FNO
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5,7-dibromo-6-fluoro-3,4-dihydro-2-methyl-1(2H)-quinolinecarboxaldehyde

参考文献

1. Courilleau D, et al. J Biol Chem. 2012 Dec 28;287(53):44192-202.

2. Courilleau D, et al. Biochem Biophys Res Commun. 2013 Oct 25;440(3):443-8.

3. Brown LM, et al. J Biol Chem. 2014 Mar 21;289(12):8217-30.

CE3F4 (EPAC1 inhibitor CE3F4)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

CE3F4 (EPAC1 inhibitor CE3F4)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.