欢迎访问ProbeChem中文网站,英文网站请访问www.probechem.com

首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Cyclin-dependent Kinase (CDK)-CDK9-IN-4d
CDK9-IN-4d

Chemical Structure : CDK9-IN-4d

CAS No.: 2105956-51-0

CDK9-IN-4d

货号: PC-62848Not For Human Use, Lab Use Only.

CDK9-IN-4d is a highly potent, selective CDK9 inhibitor with IC50 of 12 nM, shows good selectivity in CDKs kinase profiling assay against CDK kinases and cell proliferation inhibition.

规格 价格 库存 数量
5 mg Get quote
10 mg Get quote

大包装,大折扣!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    CDK9-IN-4d is a highly potent, selective CDK9 inhibitor with IC50 of 12 nM, shows good selectivity in CDKs kinase profiling assay against CDK kinases and cell proliferation inhibition.
    CDK9-IN-4d blocks the cell cycle both in G0/G1 and G2/M phase to prevent the proliferation and differentiation of cancer cells.
    CDK9-IN-4d significantly suppresses cancer with low toxicity in mice bared-breast cancer.

    物理化学性质&存储条件

    分子量 569.641
    分子式 C31H32FN7O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(4-((7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide

    参考文献

    1. Li Y, et al. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3231-3237.

    备案号:沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    联系我们 sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    询单

    • *产品名称:
    • *姓名:
    • *邮箱:
    • *公司名称:
    • *询单数量:
    • *国籍:
    • 询单信息: