Chemical Structure : CDK9-IN-4d
货号: PC-62848Not For Human Use, Lab Use Only.
CDK9-IN-4d is a highly potent, selective CDK9 inhibitor with IC50 of 12 nM, shows good selectivity in CDKs kinase profiling assay against CDK kinases and cell proliferation inhibition.
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CDK9-IN-4d is a highly potent, selective CDK9 inhibitor with IC50 of 12 nM, shows good selectivity in CDKs kinase profiling assay against CDK kinases and cell proliferation inhibition.
CDK9-IN-4d blocks the cell cycle both in G0/G1 and G2/M phase to prevent the proliferation and differentiation of cancer cells.
CDK9-IN-4d significantly suppresses cancer with low toxicity in mice bared-breast cancer.
分子量 | 569.641 | |
分子式 | C31H32FN7O3 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
1. Li Y, et al. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3231-3237.
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