CDK8 inhibitor 32

Chemical Structure : CDK8 inhibitor 32

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货号: PC-20219Not For Human Use, Lab Use Only.

CDK8 inhibitor 32 is a potent selective CDK8 inhibitor with IC50 of 1.5 nM, reduces phosphorylation of the known CDK8 substrate STAT1 in a manner identical to a CDK8 knockout clone.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

CDK8 inhibitor 32 is a potent selective CDK8 inhibitor with IC50 of 1.5 nM, reduces phosphorylation of the known CDK8 substrate STAT1 in a manner identical to a CDK8 knockout clone.

物理化学性质&存储条件

分子量	319.76
分子式	C14H10ClN3O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	7-amino-4-(4-chlorophenoxy)thieno[2,3-c]pyridine-2-carboxamide

参考文献

1. Koehler MF, et al. ACS Med Chem Lett. 2016 Jan 6;7(3):223-8.