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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Cyclin-dependent Kinase (CDK)-CDK2 inhibitor 73
CDK2 inhibitor 73

Chemical Structure : CDK2 inhibitor 73

CAS No.: 2079895-42-2

CDK2 inhibitor 73 (CDK2-IN-4)

货号: PC-61136Not For Human Use, Lab Use Only.

CDK2 inhibitor 73 (CDK2-IN-4) is a potent, selective CDK2 inhibitor with IC50 of 44 nM for CDK2/cyclin A, displays 2,000-fold selectivity over CDK1/cyclin B (IC50=86 uM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CDK2 inhibitor 73 (CDK2-IN-4) is a potent, selective CDK2 inhibitor with IC50 of 44 nM for CDK2/cyclin A, displays 2,000-fold selectivity over CDK1/cyclin B (IC50=86 uM).

物理化学性质&存储条件

分子量 442.497
分子式 C23H18N6O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-((6-([1,1'-biphenyl]-3-yl)-9H-purin-2-yl)amino) benzenesulfonamide

参考文献

1. Coxon CR, et al. J Med Chem. 2017 Mar 9;60(5):1746-1767.

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