CDK11 inhibitor 37

Chemical Structure : CDK11 inhibitor 37

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货号: PC-26429Not For Human Use, Lab Use Only.

CDK11 inhibitor 37 is a potent, selective CDK11 inhibitor with IC50 of 4 nM, exhibits clean kinome selectively.

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250 mg		Get quote

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生物&药学活性

CDK11 inhibitor 37 is a potent, selective CDK11 inhibitor with IC50 of 4 nM, exhibits clean kinome selectively.
CDK11 inhibitor 37 shows potent GI50 values of 3.7 and 0.4 μM in KHOS and LU99 cells.

物理化学性质&存储条件

分子量	337.40
分子式	C19H20FN5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((3S,5S)-5-fluoropiperidin-3-yl)-4-(1-phenyl-1H-pyrrol-3-yl)pyrimidin-2-amine

参考文献

1. Mak FS, et al. ChemMedChem. 2026 Mar 27;21(6):e202500882.