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首页-小分子抑制剂&激动剂-Epigenetics-Histone Methyltransferase (HMTase)-CDIBA
CDIBA

Chemical Structure : CDIBA

CAS No.: 479422-22-5

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CDIBA

货号: PC-49683Not For Human Use, Lab Use Only.

CDIBA is an allosteric inhibitors of m6A-RNA methyltransferase, METTL3 -14 complex with IC50 of 17.3 uM, also reported as a cytosolic phospholipase A2 (cPLA2) inhibitor.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    CDIBA is an allosteric inhibitors of m6A-RNA methyltransferase, METTL3-14 complex with IC50 of 17.3 uM, also reported as a cytosolic phospholipase A2 (cPLA2) inhibitor.

    物理化学性质&存储条件

    分子量 496.00
    分子式 C31H26ClNO3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    4-(2-(1-benzhydryl-5-chloro-2-methyl-1H-indol-3-yl)ethoxy)benzoic acid

    参考文献

    1. Je-Heon Lee, et al. Drug Dev Res. 2022 May;83(3):783-799.

    2. Supinski GS,et al. Am J Physiol Lung Cell Mol Physiol. 2016 May 15;310(10):L975-84.

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