CD73 inhibitor Compound 73

Chemical Structure : CD73 inhibitor Compound 73

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货号: PC-27237Not For Human Use, Lab Use Only.

CD73 inhibitor Compound 73 is a potent and selective non-nucleotide small molecule inhibitor of CD73 (ecto-5′-nucleotidase, eN) with IC50 of 12 nM.

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CD73 inhibitor Compound 73 is a potent and selective non-nucleotide small molecule inhibitor of CD73 (ecto-5′-nucleotidase, eN) with IC50 of 12 nM.

分子量	434.44
分子式	C24H15FN8
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-({5-[4-fluoro-1-(2H-indazol-6-yl)-1H-1,2,3-benzotriazol-6-yl]-1H-pyrazol-1-yl}methyl)benzonitrile

1. Joel W Beatty, et al. J Med Chem. 2020 Apr 23;63(8):3935-3955.