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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-RAR/RXR-CD3254
CD3254

Chemical Structure : CD3254

CAS No.: 196961-43-0

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CD3254 (CD-3254, CD 3254)

货号: PC-20829Not For Human Use, Lab Use Only.

CD3254 (CD 3254) is a potent and selective RXR agonist with EC50 of 13 nM.

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5 mg ￥880 In stock
10 mg ￥1280 In stock
25 mg ￥2180 In stock
50 mg ￥3580 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CD3254 (CD 3254) is a potent and selective RXR agonist with EC50 of 13 nM.
CD3254 stimulates RXR-regulated transcription in mammalian 2 hybrid and RXRE-mediated assays.

物理化学性质&存储条件

分子量 364.49
分子式 C24H28O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(E)-3-[3-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-4-hydroxyphenyl]acrylic acid

参考文献

1. Jin Y, et al. Proc Natl Acad Sci U S A. 2023 May 23;120(21):e2215155120.

2. Pérez Santín E, et al. J Med Chem. 2009 May 28;52(10):3150-8.

3. Bernardon JM. Int Patent Appl. 1997 WO9733881.

4. Jurutka PW, et al. J Med Chem. 2013 Nov 14;56(21):8432-54.

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