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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-RAR/RXR-CD2665
CD2665

Chemical Structure : CD2665

CAS No.: 170355-78-9

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CD2665 (CD 2665)

货号: PC-21835Not For Human Use, Lab Use Only.

CD2665 is a potent, selective and orally active RAR-β/ RAR-γ antagonist with Ki of 306 and 110 nM, respectively.

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10 mg ￥1480 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CD2665 is a potent, selective and orally active RAR-β/ RAR-γ antagonist with Ki of 306 and 110 nM, respectively.
CD2665 inhibits RA receptor-dependent gene transcription, blocks retinoid induction of RA 4-hydroxylase.

物理化学性质&存储条件

分子量 486.61
分子式 C31H34O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-(7-(adamantan-1-yl)-6-((2-methoxyethoxy)methoxy)naphthalen-2-yl)benzoic acid

参考文献

1. Kim MJ, et al. J Invest Dermatol. 2000 Feb;114(2):349-53.

2. Koyama E, et al. J Bone Miner Res. 2021 Jul;36(7):1387-1402.

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