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首页-小分子抑制剂&激动剂-GPCR-Chemokine Receptor (CCR and CXCR)-CCX2553
CCX2553

Chemical Structure : CCX2553

CAS No.: N/A

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CCX2553 (CCX-2553;CCX 2553)

货号: PC-60240Not For Human Use, Lab Use Only.

CCX2553 is a potent and specific CCR6 antagonist.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    CCX2553 is a potent and specific CCR6 antagonist.
    CCX2553 shows effectivity in murine models of psoriasis, ameliorates skin inflammation in both the IL-23-induced ear swelling model and the topical imiquimod model, and significantly reduces the number of γδT17 cells in inflamed skin.

    物理化学性质&存储条件

    分子量
    分子式
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    参考文献

    1. Campbell JJ, et al. J Immunol. 2017 Nov 1;199(9):3129-3136.

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