CCX-354 |CAS:1010073-75-2 Probechem Biochemicals

Chemical Structure : CCX-354

CAS No.: 1010073-75-2

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CCX-354 (GSK-2941266;CCX354;CCX354-C)

货号: PC-35832Not For Human Use, Lab Use Only.

CCX-354 (GSK-2941266, CCX354-C, CCX354) is a potent, selective, orally-available CCR1 antagonist for the treatment of inflammatory diseases such as rheumatoid arthritis (RA).

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5 mg	￥4780	In stock
10 mg	￥7580	In stock
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生物&药学活性

CCX-354 (GSK-2941266, CCX354-C, CCX354) is a potent, selective, orally-available CCR1 antagonist for the treatment of inflammatory diseases such as rheumatoid arthritis (RA).

物理化学性质&存储条件

分子量	451.915
分子式	C22H22ClN7O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(3-(1H-imidazol-2-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl)-1-(4-(4-chloro-3-methoxyphenyl)piperazin-1-yl)ethan-1-one

参考文献

1. Tak PP, et al. Ann Rheum Dis. 2013 Mar;72(3):337-44.

2. Harcken C, et al. Bioorg Med Chem Lett. 2018 Nov 9. pii: S0960-894X(18)30880-1.

CCX-354 (GSK-2941266;CCX354;CCX354-C)

生物&药学活性

物理化学性质&存储条件

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CCX-354 (GSK-2941266;CCX354;CCX354-C)

生物&药学活性

物理化学性质&存储条件

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