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首页-小分子抑制剂&激动剂-GPCR-Chemokine Receptor (CCR and CXCR)-CCR1 inhibitor 19e
CCR1 inhibitor 19e

Chemical Structure : CCR1 inhibitor 19e

CAS No.: 1220026-26-5

CCR1 inhibitor 19e

货号: PC-35940Not For Human Use, Lab Use Only.

CCR1 inhibitor 19e is a novel potent, selective CCR1 antagonist with IC50 of 6.8 nM, inhibits CCR1chemotaxis in THP-1 cells with IC50 of 28 nM..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CCR1 inhibitor 19e is a novel potent, selective CCR1 antagonist with IC50 of 6.8 nM, inhibits CCR1chemotaxis in THP-1 cells with IC50 of 28 nM.

物理化学性质&存储条件

分子量 425.438
分子式 C20H16FN5O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(4-fluorophenyl)-N-((2-(methylsulfonyl)pyridin-4-yl)methyl)-1H-pyrazolo[3,4-c]pyridine-4-carboxamide

参考文献

1. Harcken C, et al. Bioorg Med Chem Lett. 2018 Dec 13. pii: S0960-894X(18)30958-2. doi: 10.1016/j.bmcl.2018.12.024.

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