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首页-小分子抑制剂&激动剂-Others-GRK (GPCRK)-CCG 224061
CCG 224061

Chemical Structure : CCG 224061

CAS No.: 2055990-82-2

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CCG 224061 (CCG224061;CCG-224061)

货号: PC-60587Not For Human Use, Lab Use Only.

A potent, relatively selective G protein-coupled receptor kinase GRK2 inhibitor with IC50 of 66 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    CCG 224061 is a potent, relatively selective G protein-coupled receptor kinase GRK2 inhibitor with IC50 of 66 nM.
    CCG 224061 displays >30-fold selectivity over GRK5, GRK1, PKA and ROCK1.

    物理化学性质&存储条件

    分子量 325.387
    分子式 C19H20FN3O
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    5-(((3S,4R)-4-(4-fluorophenyl)piperidin-3-yl)methoxy)-1H-indazole

    参考文献

    1. Bouley R, et al. Mol Pharmacol. 2017 Dec;92(6):707-717.

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