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首页-小分子抑制剂&激动剂-Others-Other Targets-CCG-232601
CCG-232601

Chemical Structure : CCG-232601

CAS No.: 1922099-21-5

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CCG-232601 (CCG232601)

货号: PC-62824Not For Human Use, Lab Use Only.

CCG-232601 is a potent (IC50=0.55 uM), orally bioavailable inhibitor of Rho/MRTF/SRF transcriptional pathway that target transcriptional factor MRTF.

规格 价格 库存 数量
5 mg ￥3980 In stock
10 mg ￥5880 In stock
50 mg Get quote
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CCG-232601 is a potent (IC50=0.55 uM), orally bioavailable inhibitor of Rho/MRTF/SRF transcriptional pathway that target transcriptional factor MRTF.
CCG-232601 inhibits the development of bleomycin-induced dermal fibrosis in mice when administered at 50mg/kg.

物理化学性质&存储条件

分子量 455.89
分子式 C24H20ClF2N3O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(4-chlorophenyl)-5,5-difluoro-1-(3-(pyridin-4-yl)benzoyl)piperidine-3-carboxamide

参考文献

1. Hutchings KM, et al. Bioorg Med Chem Lett. 2017 Apr 15;27(8):1744-1749.

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