CCG-102487 | Streptokinase inhibitor | Probechem Biochemicals

Chemical Structure : CCG-102487

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CCG-102487 (CCG102487)

货号: PC-62027Not For Human Use, Lab Use Only.

CCG 102487 is a CCG-2979 analog that reduces streptokinase (SK) activity with little inhibition of group A streptococcal (GAS) growth.

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生物&药学活性

CCG-102487 is a CCG-2979 analog that reduces streptokinase (SK) activity with little inhibition of group A streptococcal (GAS) growth.
CCG-102487 alters the transcript level for key GAS virulence genes, including multiple adhesins (fibronectin binding proteins, collagen-like surface protein, laminin-binding surface protein, and M protein), cytolytic toxins (streptolysins O and S), secreted extracellular proteases (Mac, C5a peptidase, and SpeB), streptodornase Sda1 (DNase), complement inhibitor protein, and streptokinase.

物理化学性质&存储条件

分子量	428.594
分子式	C27H28N2OS
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-benzylsulfanyl-3-prop-2-enylspiro[6H-benzo[h]quinazoline-5,1'-cyclohexane]-4-one

参考文献

1. Sun H, et al. Proc Natl Acad Sci U S A. 2012 Feb 28;109(9):3469-74.

CCG-102487 (CCG102487)

生物&药学活性

物理化学性质&存储条件

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CCG-102487 (CCG102487)

生物&药学活性

物理化学性质&存储条件

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