CCF0054500 | OR2L13 agonist | Probechem Biochemicals

Chemical Structure : CCF0054500

加入收藏

CCF0054500 (CCF-0054500)

货号: PC-26506Not For Human Use, Lab Use Only.

CCF0054500 is a specific small molecule agonist of orphan GPCR OR2L13, inhibits inhibit platelet aggregation in platelet-rich plasma (PRP) with EC50 of 14 uM.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

CCF0054500 is a specific small molecule agonist of orphan GPCR OR2L13, inhibits inhibit platelet aggregation in platelet-rich plasma (PRP) with EC50 of 14 uM.
CCF0054500 broadly inhibits platelet reactivity through PAR1, P2Y12, GPVI (glycoprotein VI), and thromboxane receptors, as well as GPIIb/IIIa, uniquely inhibiting both biochemical and biomechanical activation of the platelet.phosphorylated platelet HSP27 (heat shock protein 27), disrupting the actin cytoskeleton and reducing clot retraction.
CCF0054500 reorganizes the platelet actin cytoskeleton by promoting F-actin depolymerization without diminishing the cytoskeleton globular actin pool, thereby modulating thrombosis-related platelet shape change while preserving physiologic hemostatic function.

物理化学性质&存储条件

分子量	400.54
分子式	C22H28N2O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	ethyl 5,5,7,7-tetramethyl-2-(2-phenylacetamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate

参考文献

1. Anu Aggarwal, et al. Circulation. 2026 Apr 7. doi: 10.1161/CIRCULATIONAHA.

CCF0054500 (CCF-0054500)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

CCF0054500 (CCF-0054500)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.