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CCCP

Chemical Structure : CCCP

CAS No.: 555-60-2

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CCCP (Carbonyl cyanide 3-chlorophenyl-hydrazone)

货号: PC-22180Not For Human Use, Lab Use Only.

CCCP is a small molecule mitochondrial uncoupler of oxidative phosphorylation (OXPHOS), induces activation of PINK1 leading to Parkin Ser65 phosphorylation, proton ionophore and mitophagy inducer.

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50 mg ￥1980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CCCP is a small molecule mitochondrial uncoupler of oxidative phosphorylation (OXPHOS), induces activation of PINK1 leading to Parkin Ser65 phosphorylation, proton ionophore and mitophagy inducer.

物理化学性质&存储条件

分子量 204.62
分子式 C9H5ClN4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Carbonyl cyanide 3-chlorophenyl-hydrazone

参考文献

1. Kwon D, et al. Biochem Biophys Res Commun. 2017 Aug 30. pii: S0006-291X(17)31704-7.

2. Sinha D, et al. Sci Rep. 2017 Mar 17;7:44419.

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