CC-90001 (BMS-986360) | JNK inhibitor | Probechem Biochemicals

Chemical Structure : CC-90001

CAS No.: 1403859-14-2

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CC-90001 (CC90001, BMS-986360)

货号: PC-27739Not For Human Use, Lab Use Only.

CC-90001 (BMS-986360) is a potent c-Jun N-terminal kinase (JNK) inhibitor with IC50 of 11 nM and 31 nM for JNK1 and JNK2 respectively, inhibits cellular phosphorylation of the direct JNK substrate c-Jun (p-cJun) with IC50 of 0.48 uM.

规格	价格	库存
5 mg	￥780	In stock
10 mg	￥1180	In stock
25 mg	￥1980	In stock
50 mg	￥2980	In stock
100 mg		Get quote

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生物&药学活性

CC-90001 (BMS-986360) is a potent c-Jun N-terminal kinase (JNK) inhibitor with IC50 of 11 nM and 31 nM for JNK1 and JNK2 respectively, inhibits cellular phosphorylation of the direct JNK substrate c-Jun (p-cJun) with IC50 of 0.48 uM.

物理化学性质&存储条件

分子量	321.43
分子式	C16H27N5O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(tert-Butylamino)-4-(((1R,3R,4R)-3-hydroxy-4-methylcyclohexyl)amino)pyrimidine-5-carboxamide

参考文献

1. Nagy MA, et al. J Med Chem. 2021 Dec 23;64(24):18193-18208.

2. Popmihajlov Z, et al. BMJ Open Respir Res. 2022 Jan;9(1):e001060.

CC-90001 (CC90001, BMS-986360)

生物&药学活性

物理化学性质&存储条件

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CC-90001 (CC90001, BMS-986360)

生物&药学活性

物理化学性质&存储条件

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