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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Influenza Virus-CBS1117
CBS1117

Chemical Structure : CBS1117

CAS No.: 959245-08-0

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CBS1117 (CBS-1117)

货号: PC-47054Not For Human Use, Lab Use Only.

CBS1117 is a small molecule entry inhibitor of avian influenza hemagglutinin, exhibits EC50 of 70 nM against against A/Puerto Rico/8/34 (H1N1) infection in A549 cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CBS1117 is a small molecule entry inhibitor of avian influenza hemagglutinin, exhibits EC50 of 70 nM against against A/Puerto Rico/8/34 (H1N1) infection in A549 cells.
CBS1117 specifically inhibits group 1 IAVs, likely by interfering with the HA-mediated viral-host membrane fusion.

物理化学性质&存储条件

分子量 315.238
分子式 C15H20Cl2N2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2,6-Dichloro-N-[1-(1-methylethyl)-4-piperidinyl]benzamide

参考文献

1. Amira F A Hussein, et al. Antiviral Res. 2020 May;177:104782.

2. Aleksandar Antanasijevic, et al. Life Sci Alliance. 2020 Jul 1;3(8):e202000724.

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