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CBR703

Chemical Structure : CBR703

CAS No.: 288246-39-9

CBR703 (C0340703)

货号: PC-26174Not For Human Use, Lab Use Only.

CBR703 (C0340703) is a specific small molecule bacterial RNA polymerase (RNAP) inhibitor, inhibits catalytic activities of RNAP but not translocation of RNA or DNA, inhibits nucleotide addition.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CBR703 (C0340703) is a specific small molecule bacterial RNA polymerase (RNAP) inhibitor, inhibits catalytic activities of RNAP but not translocation of RNA or DNA, inhibits nucleotide addition.

物理化学性质&存储条件

分子量 280.25
分子式 C14H11F3N2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-Hydroxy-N′-phenyl-3-(trifluoromethyl)benzenecarboximidamide

参考文献

1. Artsimovitch I, et al. A new class of bacterial RNA polymerase inhibitor affects nucleotide addition. Science. 2003 Oct 24;302(5645):650-4.

2. Villain-Guillot P, et al. Antimicrob Agents Chemother. 2007 Sep;51(9):3117-21.

3. Malinen AM, et al. Nat Commun. 2014 Mar 6;5:3408.

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