CBR-5884 |CAS:681159-27-3 Probechem Biochemicals

Chemical Structure : CBR-5884

CAS No.: 681159-27-3

加入收藏

CBR-5884 (CBR 5884;CBR5884)

货号: PC-42027Not For Human Use, Lab Use Only.

CBR-5884 (CBR5884) is a potent, selective, noncompetitive inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) with IC50 of 7 uM.

规格	价格	库存
10 mg	￥880	In stock
25 mg	￥1480	In stock
50 mg	￥2580	In stock
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

CBR-5884 (CBR5884) is a potent, selective, noncompetitive inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) with IC50 of 7 uM.
CBR-5884 selectively inhibits de novo serine synthesis in cancer cells with IC50 of 30 uM.
CBR-5884 shows a time-dependent onset of inhibition and disrupted the oligomerization state of PHGDH.

物理化学性质&存储条件

分子量	336.3861
分子式	C14H12N2O4S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Thiophenecarboxylic acid, 5-[(2-furanylcarbonyl)amino]-3-methyl-4-thiocyanato-, ethyl ester

参考文献

1. Mullarky E, et al. Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1778-83.

CBR-5884 (CBR 5884;CBR5884)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

CBR-5884 (CBR 5884;CBR5884)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.