CBP bromodomain inhibitor 27 | CBP bromodomain inhibitor

Chemical Structure : CBP bromodomain inhibitor 27

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CBP bromodomain inhibitor 27 (CBP-IN-27)

货号: PC-21984Not For Human Use, Lab Use Only.

CBP-IN-27 is a potent, selective CBP bromodomain inhibitor with IC50 of 3.6 nM, displays exquisite selectivity over BRD4(1) (IC50=11 uM) and the broader bromodomain family.

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CBP-IN-27 is a potent, selective CBP bromodomain inhibitor with IC50 of 3.6 nM, displays exquisite selectivity over BRD4(1) (IC50=11 uM) and the broader bromodomain family.

物理化学性质&存储条件

分子量	508.57
分子式	C27H30F2N6O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	6-(7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-1,3-dimethyl-4-morpholino-1,3-dihydro-2H-benzo[d]imidazol-2-one

参考文献

1. Bronner SM, et al. J Med Chem. 2017 Dec 28;60(24):10151-10171.

CBP bromodomain inhibitor 27 (CBP-IN-27)

生物&药学活性

物理化学性质&存储条件

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CBP bromodomain inhibitor 27 (CBP-IN-27)

生物&药学活性

物理化学性质&存储条件

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