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首页-小分子抑制剂&激动剂-Others-Other Targets-CBK034026C
CBK034026C

Chemical Structure : CBK034026C

CAS No.:

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CBK034026C (CBK 034026C)

货号: PC-49150Not For Human Use, Lab Use Only.

CBK034026C is a small molecule targeting metabolic vulnerabilities caused by N-acetyltransferase 2 (NAT2) activity, exhibits specific toxicity towards colorectal cancer (CRC) cells with high NAT2 activity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    CBK034026C is a small molecule targeting metabolic vulnerabilities caused by N-acetyltransferase 2 (NAT2) activity, exhibits specific toxicity towards colorectal cancer (CRC) cells with high NAT2 activity.
    CBK034026C activated the Nf-kB pathway, which is similar to ouabain, a potent inhibitor of the Na+/K+-ATPase.

    物理化学性质&存储条件

    分子量 468.583
    分子式 C23H31F3N4OS
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    5-(((1-butylpiperidin-4-yl)methyl)amino)-N-cyclobutyl-7-(trifluoromethyl)thieno[3,2-b]pyridine-3-carboxamide

    参考文献

    1. Xiaonan Zhang, et al. Biochem Pharmacol. 2022 Jul 21;115184.

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