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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Adenylate Cyclase-CB-6673567
CB-6673567

Chemical Structure : CB-6673567

CAS No.: 379218-90-3

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CB-6673567 (CB6673567)

货号: PC-62711Not For Human Use, Lab Use Only.

CB-6673567 is a potent, selective Adenylyl Cyclase 1 (AC1) inhibitor with IC50 of 77 uM, displays a 2- to 4-fold isoform selectivity over AC6.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    CB-6673567 is a potent, selective Adenylyl Cyclase 1 (AC1) inhibitor with IC50 of 77 uM, displays a 2- to 4-fold isoform selectivity over AC6; blocks the choline-induced cAMP increase in hippocampal neurons.

    物理化学性质&存储条件

    分子量 346.346
    分子式 C19H14N4O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    1,3-Benzodioxol-4-ol, 5-(1'-phenyl[4,4'-bi-1H-pyrazol]-3-yl)-

    参考文献

    1. Brand CS, et al. J Pharmacol Exp Ther. 2013 Nov;347(2):265-75.

    2. Cheng Q, et al. Neuropharmacology. 2015 Aug;95:405-14.

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