CAY10583 | BLT2 agonist | Probechem Biochemicals

Chemical Structure : CAY10583

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CAY10583 (Compound A)

货号: PC-23852Not For Human Use, Lab Use Only.

CAY10583 is a potent and selective leukotriene B4 receptor type 2 (BLT2) agonist, inhibits LTB4 binding to BLT2 with IC50 of 20 nM, but not BLT1.

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100 mg		Get quote

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生物&药学活性

CAY10583 is a potent and selective leukotriene B4 receptor type 2 (BLT2) agonist, inhibits LTB4 binding to BLT2 with IC50 of 20 nM, but not BLT1.
CAY10583 induced ERK phosphorylation only in CHO-mBLT2 but not in CHO-mBLT1.
CAY10583 induces Ca2+ mobilization and phosphorylation of extracellular signal-regulated kinase through BLT2.
CAY10583 induced phosphorylation of extracellular signal-regulated kinase in primary mouse keratinocytes, induced chemotaxis in primary mouse keratinocytes.

物理化学性质&存储条件

分子量	387.48
分子式	C25H25NO3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4'-((N-phenylpentanamido)methyl)-[1,1'-biphenyl]-2-carboxylic acid

参考文献

1. Matsumoto Y, et al. J Pharmacol Exp Ther. 2020 Apr;373(1):1-9.

2. Luo L, et al. J Diabetes Complications. 2017 Jan;31(1):13-20.

3. Yoshiko Iizuka, et al. J Biol Chem. 2005 Jul 1;280(26):24816-23.

CAY10583 (Compound A)

生物&药学活性

物理化学性质&存储条件

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CAY10583 (Compound A)

生物&药学活性

物理化学性质&存储条件

参考文献

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