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首页-小分子抑制剂&激动剂-Immunology/Inflammation-PGE synthase-CAY10526
CAY10526

Chemical Structure : CAY10526

CAS No.: 938069-71-7

CAY10526 (CAY-10526)

货号: PC-38615Not For Human Use, Lab Use Only.

CAY10526 is an inhibitor of PGE2 production through the selective modulation of mPGES-1 expression, dose-dependently inhibits PGE2 production in LPS-stimulated RAW 264.7 cells with IC50 of 1.8 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CAY10526 is an inhibitor of PGE2 production through the selective modulation of mPGES-1 expression, dose-dependently inhibits PGE2 production in LPS-stimulated RAW 264.7 cells with IC50 of 1.8 uM.

物理化学性质&存储条件

分子量 311.15
分子式 C12H7BrO3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-Benzo[b]thien-2-yl-3-bromo-5-hydroxy-2(5H)-furanone

参考文献

1. Claveau, D., et al. J. Immunol. 170, 4738-4744 (2003).

2. Guay, J., et al. J. Biol. Chem. 279(23), 24866-24872 (2004).

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