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首页-小分子抑制剂&激动剂-GPCR-Free Fatty Acid Receptor (FFAR)-CATPB
CATPB

Chemical Structure : CATPB

CAS No.: 1322598-09-3

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CATPB

货号: PC-24796Not For Human Use, Lab Use Only.

CATPB is a potent, selective free fatty acid receptor 2 (FFA2R, GPR43) antagonist with cAMP pIC50 of 6.96 and GTPγS pIC50 of 6.68, shows inverse agonist properties.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CATPB is a potent, selective free fatty acid receptor 2 (FFA2R, GPR43) antagonist with cAMP pIC50 of 6.96 and GTPγS pIC50 of 6.68, shows inverse agonist properties.

物理化学性质&存储条件

分子量 399.79
分子式 C19H17ClF3NO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-3-(2-(3-Chlorophenyl)acetamido)-4-(4-(trifluoromethyl)phenyl)butanoic acid

参考文献

1. Björkman L, et al. Mol Cell Biol. 2016 Sep 26;36(20):2583-95.

2. Park BO, et al. Eur J Pharmacol. 2016 Jan 15;771:1-9.

3. Valentini A, et al. J Med Chem. 2023 May 11;66(9):6105-6121.

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