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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Potassium Channel-CAT335
CAT335

Chemical Structure : CAT335

CAS No.: 3032789-44-6

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CAT335 (CAT-335)

货号: PC-22741Not For Human Use, Lab Use Only.

CAT335 is a small molecule covalent K2P2.1 (TREK-1) channel activator, selectively and irreversibly activates K2P2.1(TREK-1) S131C variant (TREK-1CG∗), but not wild-type K2P2.1(TREK-1)

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CAT335 is a small molecule covalent K2P2.1 (TREK-1) channel activator, selectively and irreversibly activates K2P2.1(TREK-1) S131C variant (TREK-1CG∗), but not wild-type K2P2.1(TREK-1)

物理化学性质&存储条件

分子量 375.21
分子式 C18H12Cl2N2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(2,4-dichlorobenzyl)-4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzamide

参考文献

1. Deal PE, et al. Cell Chem Biol. 2024 Jul 18;31(7):1305-1323.e9.

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