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首页-小分子抑制剂&激动剂-Epigenetics-Histone Methyltransferase (HMTase)-CARM1 inhibitor 9
CARM1 inhibitor 9

Chemical Structure : CARM1 inhibitor 9

CAS No.: 2180931-09-1

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CARM1 inhibitor 9

货号: PC-35042Not For Human Use, Lab Use Only.

CARM1 inhibitor 9 is a potent, selective inhibitor of arginine methyltransferase 1 (CARM1, PRMT4) with IC50 of 94 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    CARM1 inhibitor 9 is a potent, selective inhibitor of arginine methyltransferase 1 (CARM1, PRMT4) with IC50 of 94 nM.
    CARM1 inhibitor 9 displays 20-fold selective for CARM1 over PRMT6 and highly selective over PRMT1, PRMT3, PRMT8 as well as PRMT5 and PRMT7.
    CARM1 inhibitor 9 is a useful tool for studying the role of CARM1 in health and disease.

    物理化学性质&存储条件

    分子量 326.282
    分子式 C15H24BrN3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(3-bromobenzyl)-1-(2-(methylamino)ethyl)piperidin-4-amine

    参考文献

    1. Kaniskan HÜ, et al. Medchemcomm. 2016 Sep 1;7(9):1793-1796.

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