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首页-小分子抑制剂&激动剂-Others-Other Targets-C67-47
C67-47

Chemical Structure : C67-47

CAS No.: 1185003-32-0

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C67-47

货号: PC-27321Not For Human Use, Lab Use Only.

C67-47 is a potent and orally efficacious Phosphoglycerate kinase 1 (PGK1) inhibitor, binds strongly to PGK1 with a dissociation constant (Kd) of 63 nM, exhibits potent antiproliferative effects in pancreatic cancer cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

C67-47 is a potent and orally efficacious Phosphoglycerate kinase 1 (PGK1) inhibitor, binds strongly to PGK1 with a dissociation constant (Kd) of 63 nM, exhibits potent antiproliferative effects in pancreatic cancer cells.

物理化学性质&存储条件

分子量 403.47
分子式 C18H17N3O4S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-cyclohexyl-5-oxo-1-thioxo-4,5-dihydro-1H-[1,3]dioxolo[4,5-g]thiazolo[3,4-a]quinazoline-3-carboxamide

参考文献

1. Lihua Liu, et al. J Med Chem. 2026 Jun 11;69(11):12955-12972.

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