Chemical Structure : C450-0730
CAS No.: 1036730-46-7
货号: PC-62656Not For Human Use, Lab Use Only.
C450-0730 is a potent LuxN antagonist that antagonizes LuxN-AI-1 binding with IC50 of 2.7 uM.
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C450-0730 is a potent LuxN antagonist that antagonizes LuxN-AI-1 binding with IC50 of 2.7 uM.
C450-0730 competes for the AI-1 binding site of LuxN.
Inhibition for mutant LuxN G271D, R245L, and S184N is similar to that required to inhibit wild-type LuxN.
分子量 | 478.004 | |
分子式 | C23H28ClN3O4S | |
外观性状 | Solid | |
储存条件 |
|
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Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
2-((1-acetylindoline)-5-sulfonamido)-N-(4-chlorobenzyl)-4-methylpentanamide |
1. Swem LR, et al. Cell. 2008 Aug 8;134(3):461-73.
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