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C450-0730

Chemical Structure : C450-0730

CAS No.: 1036730-46-7

C450-0730 (LuxN antagonist)

货号: PC-62656Not For Human Use, Lab Use Only.

C450-0730 is a potent LuxN antagonist that antagonizes LuxN-AI-1 binding with IC50 of 2.7 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

C450-0730 is a potent LuxN antagonist that antagonizes LuxN-AI-1 binding with IC50 of 2.7 uM.
C450-0730 competes for the AI-1 binding site of LuxN.
Inhibition for mutant LuxN G271D, R245L, and S184N is similar to that required to inhibit wild-type LuxN.

物理化学性质&存储条件

分子量 478.004
分子式 C23H28ClN3O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-((1-acetylindoline)-5-sulfonamido)-N-(4-chlorobenzyl)-4-methylpentanamide

参考文献

1. Swem LR, et al. Cell. 2008 Aug 8;134(3):461-73.

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