C-5401331 | TIM-3 inhibitor | Probechem Biochemicals

Chemical Structure : C-5401331

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C-5401331 (C5401331)

货号: PC-21719Not For Human Use, Lab Use Only.

C-5401331 is a small molecule T-cell immunoglobulin and mucin domain-containing protein 3 (Tim-3) inhibitor, suppresses acute myeloid leukemia (AML) cell proliferation.

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生物&药学活性

C-5401331 is a small molecule T-cell immunoglobulin and mucin domain-containing protein 3 (Tim-3) inhibitor, suppresses acute myeloid leukemia (AML) cell proliferation.
C-5401331 inhibits cell viability of THP-1 and HL-60 AML cells with IC50 of 206.6 nM and 318.10 nM respectively.
C-5401331 inhibits Tim-3 and induces early and late phase apoptosis in AML cells.

物理化学性质&存储条件

分子量	332.36
分子式	C24H12O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	dibenzo[b,def]chrysene-7,14-dione

参考文献

1. Al Shahrani M, et al. Med Oncol. 2024 Jan 24;41(3):63.

C-5401331 (C5401331)

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C-5401331 (C5401331)

生物&药学活性

物理化学性质&存储条件

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