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首页-小分子抑制剂&激动剂-GPCR-Chemokine Receptor (CCR and CXCR)-C-021 dihydrochloride
C-021 dihydrochloride

Chemical Structure : C-021 dihydrochloride

CAS No.: 1784252-84-1

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C-021 dihydrochloride (C021 dihydrochloride)

货号: PC-61983Not For Human Use, Lab Use Only.

C-021 dihydrochloride is a potent and orally bioavailable CCR4 antagonist with IC50 of 0.14 uM and 0.039 uM for inhibition of chemotaxis in human and mouse, respectively..

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5 mg ￥1280 In stock
10 mg ￥1980 In stock
25 mg ￥3280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

C-021 dihydrochloride is a potent and orally bioavailable CCR4 antagonist with IC50 of 0.14 uM and 0.039 uM for inhibition of chemotaxis in human and mouse, respectively.

物理化学性质&存储条件

分子量 540.57
分子式 C27H41N5O2.2HCl
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-([1,4'-bipiperidin]-1'-yl)-N-cycloheptyl-6,7-dimethoxyquinazolin-4-amine dihydrochloride

参考文献

1. Yokoyama K, et al. Bioorg Med Chem. 2009 Jan 1;17(1):64-73.

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