Butylphthalide | 6066-49-5 | Probechem Biochemicals

Chemical Structure : Butylphthalide

CAS No.: 6066-49-5

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Butylphthalide (3-n-Butylphthalide, DL-3-n-butylphthalide)

货号: PC-23822Not For Human Use, Lab Use Only.

Butylphthalide (3-n-Butylphthalide, NBP) is an active molecule against cerebral ischemia, shows neuroprotective activity for acute ischemic stroke.

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25 mg	￥780	In stock
50 mg	￥1180	In stock
100 mg		Get quote

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生物&药学活性

Butylphthalide (3-n-Butylphthalide, NBP) is an active molecule against cerebral ischemia, shows neuroprotective activity for acute ischemic stroke.
Butylphthalide inhibits ferroptosis and ameliorates cerebral Ischaemia-Reperfusion injury in rats by activating the Nrf2/HO-1 signalling pathway.
Butylphthalide attenuates cerebral ischemia/reperfusion injury in mice through AMPK-mediated mitochondrial fusion.
Butylphthalide improves stroke outcomes after focal ischemic stroke in mouse model by inhibiting the pyroptosis-regulated cell death and ameliorating neuroinflammation.

物理化学性质&存储条件

分子量	190.24
分子式	C12H14O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-Butylisobenzofuran-1(3H)-one

参考文献

1. Lu J, et al. Brain Res Bull. 2024 Jun 15;212:110969.

2. Wang J, et al. Front Neurol. 2024 Apr 8;15:1367973.

3. Ge M, et al. Eur J Pharmacol. 2024 Jul 5;974:176593.

Butylphthalide (3-n-Butylphthalide, DL-3-n-butylphthalide)

生物&药学活性

物理化学性质&存储条件

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Butylphthalide (3-n-Butylphthalide, DL-3-n-butylphthalide)

生物&药学活性

物理化学性质&存储条件

参考文献

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