Bulevirtide (Myrcludex B, MyrB) | HBV entry inhibitor

Chemical Structure : Bulevirtide

CAS No.: 2012558-47-1

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Bulevirtide (Myrcludex B)

货号: PC-20252Not For Human Use, Lab Use Only.

Bulevirtide (Myrcludex B, MyrB) is an acylated peptide derived from the large HBV envelope protein, inhibits virus entry and infection.

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5 mg	￥2480	In stock
10 mg	￥3980	In stock
25 mg	￥5880	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

Bulevirtide (Myrcludex B, MyrB) is an acylated peptide derived from the large HBV envelope protein, inhibits virus entry and infection.
Bulevirtide (Myrcludex B) prevents HBV or woolly monkey hepatitis B virus infection in vivo, using immunodeficient urokinase-type plasminogen activator (uPA) mice repopulated with primary human or Tupaia belangeri hepatocytes.

物理化学性质&存储条件

分子量	5398.86
分子式	C234H329N65O71
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	{Myr}-Gly-Thr-Asn-Leu-Ser-Val-Pro-Asn-Pro-Leu-Gly-Phe-Phe-Pro-Asp-His-Gln-Leu-Asp-Pro-Ala-Phe-Gly-Ala-Asn-Ser-Asn-Asn-Pro-Asp-Trp-Asp-Phe-Asn-Pro-Asn-Lys-Asp-His-Trp-Pro-Glu-Ala-Asn-Lys-Val-Gly-NH2

参考文献

1. Wisskirchen K, et al. J Clin Invest. 2019 Apr 30;129(7):2932-2945.

2. Petersen J, et al. Prevention of hepatitis B virus infection in vivo by entry inhibitors derived from the large envelope protein. Nat Biotechnol. 2008;26(3):335–341.

Bulevirtide (Myrcludex B)

生物&药学活性

物理化学性质&存储条件

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Bulevirtide (Myrcludex B)

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