Chemical Structure : Brodalumab
CAS No.: 1174395-19-7
货号: PC-Ab1079Not For Human Use, Lab Use Only.
Brodalumab (AMG-827, KHK-4827) is a human monoclonal IgG2 antibody that selectively binds to human IL-17RA and inhibits its interactions with cytokines IL-17A, IL-17F, IL-17C, IL-17A/F heterodimer and IL-25. Brodalumab has been approved for the treatment of psoriasis vulgaris, psoriatic arthritis, pustular psoriasis and psoriatic erythroderma..
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥3580 | In stock | |
5 mg | ¥7580 | In stock | |
10 mg | ¥12800 | In stock | |
100 mg | Get quote |
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Brodalumab (AMG-827, KHK-4827) is a human monoclonal IgG2 antibody that selectively binds to human IL-17RA and inhibits its interactions with cytokines IL-17A, IL-17F, IL-17C, IL-17A/F heterodimer and IL-25. Brodalumab has been approved for the treatment of psoriasis vulgaris, psoriatic arthritis, pustular psoriasis and psoriatic erythroderma.
分子量 | ||
分子式 | Human IgG2-Kappa | |
外观性状 | Solid | |
储存条件 |
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Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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Chemical Name/SMILES |
Brodalumab; Siliq; AMG-827; KHK-4827; Kyntheum; LP 0160; LUMICEF; 1174395-19-7; anti- human Interleukin 17A |
1. 1, Papp KA, et al. N Engl J Med. 2012 Mar 29;366(13):1181-9. 2, Spuls PI, et al. Br J Dermatol. 2012 Oct;167(4):710-3; discussion 714-5. 3, Martin DA, et al. Arthritis Res Ther. 2013 Oct 25;15(5):R164. 4, Kellner H. Ther Adv Musculoskelet Dis. 2013 Jun;5(3):141-52.
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