Briciclib | eIF4E inhibitor | Probechem Biochemicals

Chemical Structure : Briciclib

CAS No.: 865783-99-9

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Briciclib (ON 014185, ON014185)

货号: PC-21264Not For Human Use, Lab Use Only.

Briciclib (ON 014185) is a small molecule inhibitor of eukaryotic translation initiation factor 4E (eIF4E), downregulates the expression of eIF4E and its two complex partners eIF4A and G, as well as other eIFs (e.g. eIF1A, eIF2α, eIF3A, eIF3B, eIF5 and eIF6).

规格	价格	库存
5 mg	￥880	In stock
10 mg	￥1280	In stock
25 mg	￥2180	In stock
50 mg	￥3680	In stock
100 mg		Get quote

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生物&药学活性

Briciclib (ON 014185) is a small molecule inhibitor of eukaryotic translation initiation factor 4E (eIF4E), downregulates the expression of eIF4E and its two complex partners eIF4A and G, as well as other eIFs (e.g. eIF1A, eIF2α, eIF3A, eIF3B, eIF5 and eIF6).

物理化学性质&存储条件

分子量	474.42
分子式	C19H23O10PS
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Phenol, 2-methoxy-5-[[[(1E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]-, 1-(dihydrogen phosphate)

参考文献

1. Nicole Golob-Schwarzl, et al. J Invest Dermatol. 2023 Oct 19:S0022-202X(23)02917-2.

Briciclib (ON 014185, ON014185)

生物&药学活性

物理化学性质&存储条件

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Briciclib (ON 014185, ON014185)

生物&药学活性

物理化学性质&存储条件

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