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首页-小分子抑制剂&激动剂-GPCR-Glucagon Receptor-Brenipatide
Brenipatide

Chemical Structure : Brenipatide

CAS No.: 2408921-49-1

Brenipatide (LY-3537031, LY3537031)

货号: PC-28508Not For Human Use, Lab Use Only.

Brenipatide (LY-3537031) is a potent, dual-agonist of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors, targets central nervous system and inflammatory pathways that include receptors linked to reward and addiction in the brain.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Brenipatide (LY-3537031) is a potent, dual-agonist of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors, targets central nervous system and inflammatory pathways that include receptors linked to reward and addiction in the brain.

物理化学性质&存储条件

分子量 4891.52
分子式 C228H354N46O72
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

{d-Tyr}-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{Leu(aMe)}-Leu-Asp-Lys-{Lys(AEEA-AEEA-γGlu-C20 diacid)}-Ala-Gln-{Aib}-Glu-Phe-Ile-Glu-{Tyr(aMe)}-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

参考文献

1. Neumann J, et al. Pharmaceutics. 2026 Apr 06;18(4):447.

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