Boceprevir | HCV NS3 protease inhibitor | Probechem Biochemicals

Chemical Structure : Boceprevir

CAS No.: 394730-60-0

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Boceprevir (EBP520, SCH503034, EBP-520, SCH-503034)

货号: PC-42477Not For Human Use, Lab Use Only.

Boceprevir (EBP520, SCH503034) is a potent, selective, orally bioavailable HCV NS3 protease with Ki of 14 nM, EC90 of 350 nM in cell replicon assays.

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10 mg	￥780	In stock
25 mg	￥1280	In stock
50 mg	￥2180	In stock
100 mg	￥3580	In stock
250 mg		Get quote

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生物&药学活性

Boceprevir (EBP520, SCH503034) is a potent, selective, orally bioavailable HCV NS3 protease with Ki of 14 nM, EC90 of 350 nM in cell replicon assays.
Boceprevir displays >2000-fold selectivity over human neutrophil elastase (HNE).

物理化学性质&存储条件

分子量	519.6767
分子式	C27H45N5O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	DMSO: ≥ 10 mg/mL
Chemical Name/SMILES	3-Azabicyclo[3.1.0]hexane-2-carboxamide, N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3-[(2S)-2-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]-6,6-dimethyl-, (1R,2S,5S)-

参考文献

1. Venkatraman S, et al. J Med Chem. 2006 Oct 5;49(20):6074-86.

2. Sarrazin C, et al. Gastroenterology. 2007 Apr;132(4):1270-8.

3. Flint M, et al. Antimicrob Agents Chemother. 2009 Feb;53(2):401-11.

Boceprevir (EBP520, SCH503034, EBP-520, SCH-503034)

生物&药学活性

物理化学性质&存储条件

参考文献

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Boceprevir (EBP520, SCH503034, EBP-520, SCH-503034)

生物&药学活性

物理化学性质&存储条件

参考文献

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