Blebbistatin

Chemical Structure : Blebbistatin

CAS No.: 674289-55-5

加入收藏

货号: PC-22347Not For Human Use, Lab Use Only.

Blebbistatin is a selective non-muscle myosin II (NMII) inhibitor, promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing, and better preserves cell junctional integrity and barrier function.

规格	价格	库存
5 mg	￥780	In stock
10 mg	￥1180	In stock
25 mg	￥1980	In stock
50 mg	￥3280	In stock
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Blebbistatin is a potent and selective non-muscle myosin II (NMII) inhibitor with IC50 of 0.5-5 uM.
Blebbistatin inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly.
Blebbistatin inhibits pancreatic adenocarcinoma cellular invasiveness; inhibits some myosin II-independent processes.
Blebbistatin inhibits other activities in the absence of myosin II.

物理化学性质&存储条件

分子量	292.34
分子式	C18H16N2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3a-Hydroxy-6-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one

参考文献

1. Straight AF, et al. Science. 2003 Mar 14;299(5613):1743-7.

2. Abe M, et al. J Biol Chem. 2003 Nov 28;278(48):47707-12.

3. Duxbury MS, et al. Biochem Biophys Res Commun. 2004 Jan 23;313(4):992-7.

Blebbistatin

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Blebbistatin

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.