Bitopertin R enantiomer |CAS:845614-12-2 Probechem Biochemicals

Chemical Structure : Bitopertin R enantiomer

加入收藏

货号: PC-42707Not For Human Use, Lab Use Only.

A potent and selective GlyT1 inhibitor with EC50 of 54 nM.

获取报价单

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

A potent and selective GlyT1 inhibitor with EC50 of 54 nM; no activity for GlyT2, hERG, CYP450 enzymes above 10 uM; the R enantiomer of RG-1678.

Schizophrenia

Phase 3 Clinical

分子量	543.455
分子式	C21H20F7N3O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Methanone, [4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]-1-piperazinyl][5-(methylsulfonyl)-2-[(1R)-2,2,2-trifluoro-1-methylethoxy]phenyl]-

1. Pinard E, et al. J Med Chem. 2010 Jun 24;53(12):4603-14.

2. Alberati D, et al. Neuropharmacology. 2012 Feb;62(2):1152-61

3. Martin-Facklam M, et al. Neuropsychopharmacology. 2013 Feb;38(3):504-12.

联系我们 sales@probechem.com