Bimoclomol (BRLP-42) | HSP inducer | Probechem Biochemicals

Chemical Structure : Bimoclomol

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Bimoclomol (BRLP-42, BRLP42)

货号: PC-60546Not For Human Use, Lab Use Only.

Bimoclomol (BRLP-42) is a potent heat shock protein coinducer, increases an inducible member of the heat shock protein 70 family (HSP70) and cytoprotect in vitro, reduces infarct size in a rat model of ischemia and reperfusion.

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生物&药学活性

Bimoclomol (BRLP-42) is a potent heat shock protein coinducer, increases an inducible member of the heat shock protein 70 family (HSP70) and cytoprotect in vitro, reduces infarct size in a rat model of ischemia and reperfusion.
Bimoclomol facilitates the formation of chaperone molecules in eukaryotic cells by inducing or amplifying expression of heat-shock genes.

物理化学性质&存储条件

分子量	297.783
分子式	C14H20ClN3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-hydroxy-3-(1-piperidinyl) propoxy]-3-pyridinecarboximidoil-chloride

参考文献

1. Vígh L, et al. Nat Med. 1997 Oct;3(10):1150-4.

2. Erdö F, et al. Brain Res Bull. 1998;45(2):163-6.

3. Nánási PP, et al. Br J Pharmacol. 2000 Apr;129(7):1405-12.

4. Lubbers NL, et al. Eur J Pharmacol. 2002 Jan 18;435(1):79-83.

Bimoclomol (BRLP-42, BRLP42)

生物&药学活性

物理化学性质&存储条件

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Bimoclomol (BRLP-42, BRLP42)

生物&药学活性

物理化学性质&存储条件

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